All-in-one solution since generation, staining and analyses of 3D aggregates can be performed in one single plate. Matrix-free, High-Throughput-/High-Content-Screening compatible. Up to 16.224 3D aggregates on one MTP.
Adherent or non-adherent spheroid generation, ADME/TOX, DMPK, stem cell/iPSC-, and organoid culture applications. Moreover, plates for the analysis of whole organisms, such as zebra fish and C.elegans are available.
See references showing the successful use of microcavity arrays. Latest references show the implementation of the system as artificial stem cell niche and the use as a 3D-High-Throughput- and Screening platform for embryoid bodies.
Studies of Biology, Ph.D. in Mechanical Engineering, Head of Biomimetic Microstructures, Karlsruhe Institute of Technology, Assistant Professor, micro- and nanoengineering of complex artificial cellular microenvironments, MERLN Institute for Technology-Inspired Regenerative Medicine, Maastricht University
Studies of Biology, Ph.D. in Biochemical Pharmacology, Head of 3D-Cell Culture, Professor for Technical Biology, Karlsruhe Institute of Technology. Development of microcavity array based applications such as artificial stem cell niche, organotypic liver cultures etc.
Studies of Mechanical Engineering (Ph.D.), Head of „membrane-based polymer microfluidic sensor and actuator components“, Karlsruhe Institute of Technology, Assistant Professor, micro- and nanoengineering of complex artificial cellular microenvironments, MERLN Institute for Technology-Inspired Regenerative Medicine, Maastricht University
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